Regulatory Compliance, Industry Impact 15 Jan 2025 regulatory compliance, business impact, fda, pharmaceutical, drug approval

💊FDA Withdraws Approval of 12 Drug Applications

The Food and Drug Administration (FDA or Agency) is withdrawing approval of 12 new drug applications (NDAs) from multiple applicants. The applicants notified the Agency in writing that the drug products were no longer marketed and requested that the approval of the applications be withdrawn.

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Regulatory Compliance, Financial Opportunities 15 Jan 2025 healthcare, regulatory, fda, pharmaceutical, priority review voucher, rare diseases

💊FDA Issues Priority Review Voucher for Rare Pediatric Disease Product

The Food and Drug Administration (FDA) is announcing the issuance of a priority review voucher to the sponsor of a rare pediatric disease product application. The Federal Food, Drug, and Cosmetic Act (FD&C Act) authorizes FDA to award priority review vouchers to sponsors of approved rare pediatric disease product applications that meet certain criteria. FDA is required to publish notice of the award of the priority review voucher. FDA has determined that ALHEMO (concizumab-mtci), approved on December 20, 2024, manufactured by Novo Nordisk, Inc., meets the criteria for a priority review voucher.

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Regulatory, Compliance 10 Jan 2025 fda, pharmaceutical, priority review voucher, crinecerfont, neurocrine biosciences, rare diseases

💊FDA Issues Priority Review Voucher for CRENESSITY (Crinecerfont)

The Food and Drug Administration (FDA) is announcing the issuance of a priority review voucher to the sponsor of a rare pediatric disease product application. The Federal Food, Drug, and Cosmetic Act (FD&C Act) authorizes FDA to award priority review vouchers to sponsors of approved rare pediatric disease product applications that meet certain criteria. FDA is required to publish notice of the award of the priority review voucher. FDA has determined that CRENESSITY (crinecerfont), approved on December 13, 2024, manufactured by Neurocrine Biosciences, Inc., meets the criteria for a priority review voucher.

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Regulatory Compliance, Business Incentives 10 Jan 2025 regulatory compliance, fda, pharmaceutical, drug approval, rare pediatric disease

💊FDA Approves ALYFTREK Under Pediatric Disease Priority Program

The Food and Drug Administration (FDA) is announcing the issuance of approval of a product redeeming a priority review voucher. The Federal Food, Drug, and Cosmetic Act (FD&C Act) authorizes FDA to award priority review vouchers to sponsors of approved rare pediatric disease product applications that meet certain criteria. FDA is required to publish notice of the issuance of priority review vouchers as well as the approval of products redeeming a priority review voucher. FDA has determined that the application for ALYFTREK (vanzacaftor, tezacaftor, and deutivacaftor), approved December 20, 2024, meets the criteria for redeeming a priority review voucher.

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Regulatory Compliance, Industry Advisory 10 Jan 2025 regulatory compliance, advisory committee, fda, pharmaceutical, antimicrobial drugs

💊FDA Renews Antimicrobial Drugs Advisory Committee Through 2026

The Food and Drug Administration (FDA or the Agency) is announcing the renewal of the Antimicrobial Drugs Advisory Committee by the Commissioner of Food and Drugs (the Commissioner). The Commissioner has determined that it is in the public interest to renew the Antimicrobial Drugs Advisory Committee for an additional 2 years beyond the charter expiration date. The new charter will be in effect until the October 7, 2026, expiration date.

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Regulatory Compliance, Industry Standards 6 Jan 2025 guidance, drug products, manufacturing, pharmaceutical, fda, compliance

💊FDA Draft Guidance on Complying with 21 CFR 211.110 Available

The Food and Drug Administration (FDA or Agency) is announcing the availability of a draft guidance for industry entitled "Considerations for Complying With 21 CFR 211.110." This guidance, when finalized, will describe considerations for complying with the requirements for ensuring batch uniformity and drug product integrity. In addition, this guidance discusses related quality considerations for drug products that are manufactured using advanced manufacturing. FDA is committed to supporting and enabling pharmaceutical innovation and modernization as part of the Agency's mission to protect and promote the public health. FDA encourages industry representatives and manufactures who are interested in using innovative control strategies to contact the Agency.

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