Rule 21 Aug 2025 healthcare, regulation, fda, medical devices, pharmacogenetics

🧬FDA Classifies Pharmacogenetic Assessment System as Class II Device

The Food and Drug Administration (FDA, the Agency, or we) is classifying the pharmacogenetic assessment system into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for classification of the pharmacogenetic assessment system. We are taking this action because we have determined that classifying the device into class II will provide a reasonable assurance of safety and effectiveness of the device. We believe this action will also enhance patients' access to beneficial innovative devices, in part by reducing regulatory burdens.

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Rule 21 Aug 2025 compliance, health care, fda regulations, medical devices, gastrointestinal technology

⚙️FDA Classifies Laparoscopic Gastrointestinal Sizing Tool

The Food and Drug Administration (FDA, the Agency, or we) is classifying the laparoscopic gastrointestinal sizing tool into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for the classification of the laparoscopic gastrointestinal sizing tool. We are taking this action because we have determined that classifying the device into class II will provide a reasonable assurance of safety and effectiveness of the device. We believe this action will also enhance patients' access to beneficial innovative devices, in part by reducing regulatory burdens.

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Rule 21 Aug 2025 healthcare, regulation, fda, laboratories, medical devices, biologics, class ii

🧬FDA Classifies Postnatal Chromosomal Detection System as Class II

The Food and Drug Administration (FDA, the Agency, or we) is classifying the postnatal chromosomal copy number variation detection system into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for the postnatal chromosomal copy number variation detection system's classification. We are taking this action because we have determined that classifying the device into class II will provide a reasonable assurance of safety and effectiveness of the device. We believe this action will also enhance patients' access to beneficial innovative devices, in part by reducing regulatory burdens.

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Rule 21 Aug 2025 regulation, fda, laboratories, medical devices, health industry, biologics, bacterial vaginosis, vaginitis

🩺FDA Classifies Device for Detecting Vaginitis-Related Microorganisms

The Food and Drug Administration (FDA, the Agency, or we) is classifying the device that detects nucleic acid sequences from microorganisms associated with vaginitis and bacterial vaginosis into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for the device that detects nucleic acid sequences from microorganisms associated with vaginitis and bacterial vaginosis's classification. We are taking this action because we have determined that classifying the device into class II will provide a reasonable assurance of safety and effectiveness of the device. We believe this action will also enhance patients' access to beneficial innovative devices, in part by reducing regulatory burdens.

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Rule 21 Aug 2025 regulation, fda, food safety, medical devices, food industry, cosmetics, color additives, drugs, foods, beverage industry

🍹FDA Confirms Galdieria Extract Blue as Safe Color Additive

The Food and Drug Administration (FDA or we) is confirming the effective date of June 26, 2025, for the final order that appeared in the Federal Register of May 12, 2025. The final order amends the color additive regulations to provide for the safe use of galdieria extract blue as a color additive at levels consistent with good manufacturing practice (GMP) in: non-alcoholic beverages and beverage bases, fruit drinks, fruit smoothies, fruit juices, vegetable juices, dairy-based smoothies, milk shakes and flavored milks, yogurt drinks, milk-based meal replacement and nutritional beverages, breakfast cereal coatings, hard candy, soft candy and chewing gum, flavored frostings, ice cream and frozen dairy desserts, frozen fruits, water ices and popsicles, gelatin desserts, puddings and custards, whipped cream, yogurt, frozen or liquid creamers (including non-dairy alternatives), and whipped toppings (including non-dairy alternatives).

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Rule 21 Aug 2025 regulatory compliance, healthcare, fda, medical devices, orthopedic instruments

🩺FDA Classifies Orthopedic Surgical Instruments as Class II Devices

The Food and Drug Administration (FDA, the Agency, or we) is classifying orthopedic manual surgical instrumentation for use with non-fusion spinous process spacer devices into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for classification of orthopedic manual surgical instrumentation for use with non-fusion spinous process spacer devices. We are taking this action because we have determined that classifying the device into class II will provide a reasonable assurance of safety and effectiveness of the device. We believe this action will also enhance patients' access to beneficial innovative devices, in part by reducing regulatory burdens.

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Notice 7 Aug 2025 information collection, healthcare compliance, medical devices, public health, fda, radiation

📊FDA Seeks Comments on Communications Testing for Medical Devices

The Food and Drug Administration (FDA or Agency) is announcing an opportunity for public comment on the proposed collection of certain information by the Agency. Under the Paperwork Reduction Act of 1995 (PRA), Federal Agencies are required to publish notice in the Federal Register concerning each proposed collection of information, including each proposed extension of an existing collection of information, and to allow 60 days for public comment in response to the notice. This notice solicits comments on the generic clearance for testing communications on medical devices and radiation-emitting products by FDA's Center for Devices and Radiological Health (CDRH). This generic ICR facilitates CDRH's efforts to assess the need for communications on specific topics and to assist in the development and modification of communication messages to promote public health and compliance with regulations.

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Notice 7 Aug 2025 information collection, medical devices, humanitarian use devices, regulatory compliance, fda

🏥FDA Notice on Humanitarian Use Devices Information Collection

The Food and Drug Administration (FDA or Agency) is announcing an opportunity for public comment on the proposed collection of certain information by the Agency. Under the Paperwork Reduction Act of 1995 (PRA), Federal Agencies are required to publish notice in the Federal Register concerning each proposed collection of information, including each proposed extension of an existing collection of information, and to allow 60 days for public comment in response to the notice. This notice solicits comments on information collection related to humanitarian use devices (HUDs) and humanitarian device exemption (HDE).

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Proposed Rule 4 Aug 2025 veterans, administrative practice and procedure, veterans affairs, mental health programs, claims, health professions, health care, health facilities, government policy, health regulations, health records, medical research, medical devices, reproductive health, healthcare industry

⚕️VA Proposes Reinstatement of Abortion Exclusions in Medical Benefits

The Department of Veterans Affairs (VA) is proposing to reinstate the full exclusion on abortions and abortion counseling from the medical benefits package, which was removed in 2022. Before that time, this exclusion had been firmly in place since the medical benefits package was first established in 1999. VA is also proposing to reinstate the exclusions on abortion and abortion counseling for Civilian Health and Medical Program of the Department of Veterans Affairs (CHAMPVA) that were removed in 2022. We take this action to ensure that VA provides only needed medical services to our nation's heroes and their families.

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Notice 31 Jul 2025 regulatory compliance, small business, fda, medical devices, user fee, financial hardship

💰FDA Final Guidance on Medical Device User Fees for Small Businesses

The Food and Drug Administration (FDA or Agency) is announcing the availability of a final guidance for industry entitled "Medical Device User Fee Small Business Qualification and Determination Guidance." This guidance updates the previous version of the guidance, titled "Medical Device User Fee Small Business Qualification and Certification Guidance", issued on August 1, 2018. The guidance includes updates which describe how FDA plans to determine if a small business is experiencing "financial hardship" which makes them eligible for a waiver of their registration fee. The guidance details what information FDA intends to review and consider in making this determination.

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