Notice 19 Aug 2025 compliance, pharmaceuticals, fda, business regulations, drug approvals, nitrosamines

💊FDA Confirms RIFADIN Capsules Not Withdrawn for Safety or Effectiveness

The Food and Drug Administration (FDA or Agency) has determined that RIFADIN (rifampin) capsules, 150 milligrams (mg) and 300 mg, were not withdrawn from sale for reasons of safety or effectiveness to the extent that the drugs can be manufactured or formulated in a manner that satisfies any applicable acceptable intake limit for nitrosamine impurities. This determination means that FDA will not begin procedures to withdraw approval of abbreviated new drug applications (ANDAs) that refer to these drug products, and it will allow FDA to continue to approve ANDAs that refer to the products as long as they meet relevant legal and regulatory requirements, including satisfying any applicable acceptable intake limit for nitrosamine impurities.

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Notice 11 Aug 2025 compliance, pharmaceuticals, drug importation, dea, controlled substances

💊DEA Notice on Experic LLC's Importer Application for Controlled Substances

Experic LLC has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to Supplementary Information listed below for further drug information.

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Notice 11 Aug 2025 compliance, business regulation, pharmaceuticals, dea, controlled substances, drug enforcement

💊DEA Notice

Chattem Chemicals has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to Supplementary Information listed below for further drug information.

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Notice 11 Aug 2025 compliance, regulation, pharmaceuticals, drug importation, dea, controlled substances

💊DEA Notice

Veterans Pharmaceuticals, Inc. has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to Supplementary Information listed below for further drug information.

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Notice 11 Aug 2025 regulatory compliance, pharmaceuticals, dea, controlled substances, iowa, drug manufacturing

💊Cambrex Charles City Seeks Registration for Controlled Substance Manufacturing

Cambrex Charles City has applied to be registered as a bulk manufacturer of basic class(es) of controlled substance(s). Refer to SUPPLEMENTARY INFORMATION listed below for further drug information.

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Notice 8 Aug 2025 public meeting, regulation, pharmaceuticals, fda, manufacturing, domestic production

💊FDA Seeks Input on Onshoring Drug Manufacturing

The Food and Drug Administration (FDA, the Agency, or we) is announcing the establishment of a docket to solicit public comments on issues related to accelerating the establishment of new pharmaceutical manufacturing facilities in the United States. FDA is also announcing the following public meeting entitled "Onshoring Manufacturing of Drugs and Biological Products." At this meeting, FDA will present a draft framework that seeks to facilitate onshoring of pharmaceutical manufacturing. Participants will then engage in a guided discussion regarding the proposed framework, its strengths, weaknesses, and opportunities. The group will also discuss additional considerations that may help overcome current challenges faced by industry to onshoring the manufacturing of pharmaceuticals, including active pharmaceutical ingredients (APIs) and finished drug and biological products, and ideas and options within the bounds of FDA's statutory authority that could facilitate such onshoring of manufacturing.

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Notice 4 Aug 2025 regulation, pharmaceuticals, fda, teva pharmaceuticals, drug applications

💊FDA Notice on Withdrawal of Abbreviated New Drug Applications

The Food and Drug Administration (FDA) is correcting a notice that appeared in the Federal Register on January 15, 2025.

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Notice 4 Aug 2025 pharmaceuticals, fda, drug approval, generic drugs, acetaminophen, oxycodone

💊FDA Affirms ROXICET Availability for Generic Drug Applications

The Food and Drug Administration (FDA or Agency) has determined that ROXICET (oxycodone hydrochloride (HCl) and acetaminophen) tablet, 5 milligrams (mg)/325 mg, was not withdrawn from sale for reasons of safety or effectiveness. This determination will allow FDA to approve abbreviated new drug applications (ANDAs) for oxycodone HCl and acetaminophen tablet, 5 mg/ 325 mg, if all other legal and regulatory requirements are met.

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Notice 4 Aug 2025 regulatory compliance, pharmaceuticals, fda, public comments, prescription drug user fee act

💊FDA Reopens Comment Period on Prescription Drug User Fee Act VII

The Food and Drug Administration (FDA or the Agency) is reopening the comment period for the notice of availability entitled "Prescription Drug User Fee Act VII; Independent Assessment of Communication Through Product Quality Information Requests During Application Review; Final Report; Availability; Request for Comments" that appeared in the Federal Register of May 9, 2025. In the notice of availability, FDA requested comments on the final assessment report. The Agency is taking this action in response to a request to allow interested persons additional time to submit comments.

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Notice 4 Aug 2025 compliance, healthcare, regulations, pharmaceuticals, fda, drug approvals

💊FDA Withdraws Approval of 39 New Drug Applications

The Food and Drug Administration (FDA or Agency) is withdrawing approval of 39 new drug applications (NDAs) from multiple applicants. The applicants notified the Agency in writing that the drug products were no longer marketed and requested that the approval of the applications be withdrawn.

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