3 Jun 2025

⚖️Proposed Scheduling of 4-Fluoroamphetamine as a Schedule I Substance

Schedules of Controlled Substances: Placement of 4-Fluoroamphetamine in Schedule I

Summary

The Drug Enforcement Administration proposes placing the substance 4-fluoroamphetamine (4-FA; 1-(4-fluorophenyl)propan-2-amine), including its salts, isomers, and salts of isomers, in schedule I of the Controlled Substances Act. This action is being taken, in part, to enable the United States to meet its obligations under the 1971 Convention on Psychotropic Substances. If finalized, this action would impose the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances on persons who handle (manufacture, distribute, reverse distribute, import, export, engage in research, conduct instructional activities or chemical analysis with, or possess) or propose to handle 4-fluoroamphetamine.

Agencies

  • Justice Department
  • Drug Enforcement Administration

Business Impact ?

$$$ - High

The proposed rule to classify 4-fluoroamphetamine (4-FA) as a Schedule I controlled substance imposes significant compliance requirements on manufacturers, distributors, and researchers. Businesses would need to register with the DEA and meet stringent security, labeling, inventory, and reporting obligations, indicating direct regulatory impacts on operations and potential financial liabilities for non-compliance.

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