19 Aug 2025

💊Executive Order on Pharmaceutical Supply Chain Resilience

Ensuring American Pharmaceutical Supply Chain Resilience by Filling the Strategic Active Pharmaceutical Ingredients Reserve

Summary ?

Executive Order 14336 aims to strengthen the resilience of the American pharmaceutical supply chain by ensuring a stockpile of active pharmaceutical ingredients (APIs). It mandates the development of a critical drugs list and prioritizes domestic production, highlighting the government's efforts to enhance national security concerning essential medicines and medical countermeasures.

Agencies

  • Executive Office of the President

Business Impact ?

$$$ - High

The regulation directly impacts pharmaceutical manufacturers as it mandates the filling of the Strategic Active Pharmaceutical Ingredients Reserve (SAPIR) with domestically sourced APIs, thereby creating compliance obligations and potential financial opportunities. Specifically, sections addressing the development of a critical drugs list and preference for domestic procurement indicate financial implications for businesses involved in the production and supply of APIs.

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